{"id":12821,"date":"2022-07-14T23:26:10","date_gmt":"2022-07-14T23:26:10","guid":{"rendered":"https:\/\/unchainedlabs.com\/jp\/?page_id=12821"},"modified":"2023-02-18T01:53:47","modified_gmt":"2023-02-18T01:53:47","slug":"nunchuck","status":"publish","type":"page","link":"https:\/\/unchainedlabs.com\/jp\/nunchuck\/","title":{"rendered":"Nunchuck"},"content":{"rendered":"\n\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/07\/Nunchuck-front-rev03.png\" alt=\"Nunchuck front rev03\" itemprop=\"image\" height=\"477\" width=\"800\" title=\"Nunchuck front rev03\" onerror=\"this.style.display='none'\"  \/>\n<h1>\n\t\tNunchuck\n\t<\/h1>\n\t<p>The one-and-done LNP maker<\/p>\n\t\t\t<a href=\"https:\/\/go.unchainedlabs.com\/jp\/l\/907652\/2021-02-11\/893n\" target=\"_blank\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tRequest a quote\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2023\/02\/Nunchuck_brochure_RevB.pdf\" target=\"_blank\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tGet Brochure\n\t\t\t\t\t<\/a>\n\t<ul>\n<li>\n<ul>\n<li><a href=\"#overview\">overview<\/a><\/li>\n<li><a href=\"#capabilities\">capabilities<\/a><\/li>\n<li><a href=\"#resources\">resources<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>\n\t\tGet sweet nunchuck skills\n\t<\/h2>\n\t<p>Nunchuck is the first and only platform that combines two key steps needed to make\u00a0the perfectly-sized LNP &#8211; low-volume screening and scaled-up LNP formulation.\u00a0Screen 8 total flow rates (TFRs) in just 10 minutes to find your sweet spot fast, then\u00a0jump straight into making 0.250 mL to 1 L of your LNPs &#8211; all in the same day, on the\u00a0same consumable. Dump the one\u2011flow-rate-at-a-time, back-and-forth workflows for\u00a0the ultimate one\u2011and\u2011done LNP maker. <a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2023\/02\/Nunchuck_brochure_RevB.pdf\" target=\"_blank\" rel=\"noopener\">Get brochure<\/a>.<\/p>\n\t<ul>\n<li>0.250 mL &#8211; 1 L formulations<\/li>\n<li>Screen 8 TFRs in 10 min<\/li>\n<\/ul>\n\t<p>Want a quote or a demo?<\/p>\n\t\t\t<a href=\"https:\/\/go.unchainedlabs.com\/jp\/l\/907652\/2021-02-11\/893n\" target=\"_blank\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tGet One\n\t\t\t\t\t<\/a>\n<h2>\n\t\tThe nun gets it done\n\t<\/h2>\n\t<p>Load your syringes filled with aqueous and organic solutions into Nunchuck, lock\u00a0them into the Nun consumable, and you&#8217;re ready to start making LNPs. The Nun&#8217;s\u00a0novel <a href=\"https:\/\/unchainedlabs.com\/jp\/microfluidic-mixing\/\">microfluidic mixing chambers<\/a> can handle flow rates from 0.5 to 30 mL\/min\u00a0which means it can create a wide range of LNP sizes.\u00a0Plus the nun can be used\u00a0more than once &#8211; same day, same chemistry, same nun.<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/07\/The-nun-gets-it-done_2.png\" alt=\"The nun gets it done_2\" itemprop=\"image\" height=\"348\" width=\"800\" title=\"The nun gets it done_2\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/07\/Whitebelts-welcome_stroke.png\" alt=\"Whitebelts welcome_stroke\" itemprop=\"image\" height=\"430\" width=\"800\" title=\"Whitebelts welcome_stroke\" onerror=\"this.style.display='none'\"  \/>\n<h2>\n\t\tWhite belts welcome\n\t<\/h2>\n\t<p>Nunchuck is so easy to use a newbie can kick off a run in minutes. First, choose either\u00a0a screening or prep run, then enter all the details about your formulation. The last\u00a0step is to choose your flow rate ratio, total flow rates, and desired sample volume.\u00a0You&#8217;ll be an LNP black belt in 5 minutes flat.<\/p>\n<h2>\n\t\tHit your target\n\t<\/h2>\n\t<p>Depending on your target, you&#8217;ll need to make different sizes of LNPs. Dialing in the\u00a0total flow rate (TFR) is one of the most time-consuming steps for getting the size right.\u00a0Nunchuck is outfitted with a fit-for-purpose screening run that nails down your TFR\u00a0in 10 minutes. Screen up to 8 total flow rates with crazy repeatability so you can find\u00a0your optimal conditions without breaking a sweat.<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/07\/Hit-your-target_2.png\" alt=\"Hit your target_2\" itemprop=\"image\" height=\"650\" width=\"671\" title=\"Hit your target_2\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/07\/Level-up_2.png\" alt=\"Level up_2\" itemprop=\"image\" height=\"506\" width=\"800\" title=\"Level up_2\" onerror=\"this.style.display='none'\"  \/>\n<h2>\n\t\tLevel up\n\t<\/h2>\n\t<p>It doesn&#8217;t matter if you need\u00a00.250 mL to 1 L &#8211; Nunchuck gets you the same\u00a0high\u2011quality LNPs at any volume. Forget using one instrument to optimize your\u00a0sample and another to make enough to characterize and develop your LNP\u00a0formulations, Nunchuck always has your back.<\/p>\n<h2>\n\t\tLearn more\n\t<\/h2>\n<h2>\n\t\tWebinars\n\t<\/h2>\n\t<a href=\"https:\/\/unchainedlabs.wistia.com\/medias\/ou8020902f\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.wistia.com\/medias\/ou8020902f\"><\/a>\n\t\t\tEarn your black belt with Nunchuck&#8217;s LNP making skills\t\t\t\n\t\t\t\t<p>Martha Perez, PhD, Marketing Director, Unchained Labs<\/p>\n<h2>\n\t\tApp Notes\n\t<\/h2>\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/11\/Screen-and-prep-LNPs-with-Nunchuck_Rev-A_r2.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/11\/Screen-and-prep-LNPs-with-Nunchuck_Rev-A_r2.pdf\"><\/a>\n\t\t\tScreen and prep LNPs with Nunchuck\t\t\t\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/11\/Tech_Note_Nunchucks-fluidic-path-chemical-compatibility_Rev-A.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/11\/Tech_Note_Nunchucks-fluidic-path-chemical-compatibility_Rev-A.pdf\"><\/a>\n\t\t\tNunchuck&#8217;s fluidic path chemical compatibility\t\t\t\n<h2>\n\t\tTechnology\n\t<\/h2>\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/microfluidic-mixing\/\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/microfluidic-mixing\/\"><\/a>\n\t\t\tMicrofluidic Mixing\t\t\t\n<h2>\n\t\tWant a quote or a demo?\n\t<\/h2>\n\t\t\t<a href=\"https:\/\/go.unchainedlabs.com\/jp\/l\/907652\/2021-02-11\/893n\" target=\"_blank\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tGet One\n\t\t\t\t\t<\/a>\n<h2>\n\t\tRelated products\n\t<\/h2>\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/stunner\/\" target=\"_self\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/stunner\/\" rel=\"noopener\"><\/a>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/02\/Stunner_Uncle-product-page_3-e1658951180154.png\" alt=\"Stunner_Uncle-product-page_3\" title=\"Stunner_Uncle-product-page_3\" itemprop=\"image\"\/>\n\t\t<h3>Stunner<\/h3>\t\t\t\n\t\t\t\t<p>The ultimate gene therapy tool<\/p>\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/big-tuna\/\" target=\"_self\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/big-tuna\/\" rel=\"noopener\"><\/a>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/Big-Tuna-fron@2xt.png\" alt=\"Big-Tuna-fron@2xt\" title=\"Big-Tuna-fron@2xt\" itemprop=\"image\"\/>\n\t\t<h3>Big Tuna<\/h3>\t\t\t\n\t\t\t\t<p>The ultimate automated buffer exchange solution<\/p>\n\n","protected":false},"excerpt":{"rendered":"<p>Nunchuck The one-and-done LNP maker Request a quote Get Brochure overview capabilities resources Get sweet nunchuck skills Nunchuck is the first and only platform that combines two key steps needed to make\u00a0the perfectly-sized LNP &#8211; low-volume screening and scaled-up LNP formulation.\u00a0Screen 8 total flow rates (TFRs) in just 10 minutes to find your sweet spot&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-12821","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - 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