{"id":4403,"date":"2021-12-07T04:53:39","date_gmt":"2021-12-07T04:53:39","guid":{"rendered":"http:\/\/unchainedlabs.sheldon.com\/?page_id=4403"},"modified":"2025-01-21T02:38:30","modified_gmt":"2025-01-21T02:38:30","slug":"uncle","status":"publish","type":"page","link":"https:\/\/unchainedlabs.com\/jp\/uncle\/","title":{"rendered":"Uncle"},"content":{"rendered":"\n\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/UNcle-front-transparent_2.png\" alt=\"UNcle front-transparent_2\" itemprop=\"image\" height=\"678\" width=\"740\" title=\"UNcle front-transparent_2\" onerror=\"this.style.display='none'\"  \/>\n<h1>\n\t\tUncle\n\t<\/h1>\n\t<p>\u30aa\u30fc\u30eb\u30a4\u30f3\u30ef\u30f3 \u5b89\u5b9a\u6027\u8a55\u4fa1\u88c5\u7f6e<\/p>\n\t\t\t<a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2024\/05\/UNcle_brochure_RevG_JP.pdf\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t\t\u30ab\u30bf\u30ed\u30b0\n\t\t\t\t\t<\/a>\n\t<ul>\n<li><a href=\"#overview\">\u6982\u8981<\/a><\/li>\n<li><a href=\"#video\">\u52d5\u753b<\/a><\/li>\n<li><a href=\"#capabilities\">\u6a5f\u80fd<\/a><\/li>\n<li><a href=\"#resources\">\u95a2\u9023\u8cc7\u6599<\/a><\/li>\n<\/ul>\n<h2>\n\t\t\u30ef\u30f3\u30b9\u30c8\u30c3\u30d7\u306e\u5b89\u5b9a\u6027\u8a55\u4fa1\n\t<\/h2>\n\t<p>\u5927\u91cf\u306e\u30b5\u30f3\u30d7\u30eb\u3092\u5fc5\u8981\u3068\u3059\u308b\u30c4\u30fc\u30eb\u3092\u8907\u6570\u7528\u3044\u3066\u5b89\u5b9a\u6027\u3092\u8a55\u4fa1\u3059\u308b\u306b\u306f\u81a8\u5927\u306a\u52b4\u529b\u304c\u5fc5\u8981\u3067\u3059\u3002Uncle\u306f\u86cd\u5149\u3001SLS\u3001DLS\u3068\u3044\u30463\u3064\u306e\u7570\u306a\u308b\u6e2c\u5b9a\u30e2\u30fc\u30c9\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u3044\u307e\u3059\u306e\u3067\u3001\u308f\u305a\u304b\u6570\u6642\u9593\u3067\u3059\u3079\u3066\u306e\u30c7\u30fc\u30bf\u3092\u53d6\u5f97\u3057\u3001\u4f7f\u7528\u3059\u308b\u30b5\u30f3\u30d7\u30eb\u306e\u91cf\u3092\u5927\u5e45\u306b\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u5f97\u3089\u308c\u305f\u3059\u3079\u3066\u306e\u60c5\u5831\u3092\u7528\u3044\u3066\u3001\u6700\u9069\u306a\u51e6\u65b9\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u307e\u305f\u306f\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3092\u7c21\u5358\u306b\u9078\u629e\u3067\u304d\u307e\u3059\u3002<a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2024\/05\/UNcle_brochure_RevG_JP.pdf\">\u30ab\u30bf\u30ed\u30b0\u306f\u3053\u3061\u3089<\/a>\u3002<\/p>\n\t<ul>\n<li>T<sub>m<\/sub> &amp; T <sub>agg<\/sub><\/li>\n<li>\u7b49\u6e29\u5b89\u5b9a\u6027\n<\/li>\n<li>\u30a6\u30a4\u30eb\u30b9\u30ab\u30d7\u30b7\u30c9\u306e\u5b89\u5b9a\u6027<\/li>\n<li>SYPRO\u3092\u7528\u3044\u305fT<sub>m<\/sub>\uff08DSF\uff09<\/li>\n<li>\u30b5\u30a4\u30b8\u30f3\u30b0\u3068\u591a\u5206\u6563\u6027<\/li>\n<li>\u30b5\u30fc\u30de\u30eb\u30e9\u30f3\u30d7\u306b\u3088\u308b\u30b5\u30a4\u30b8\u30f3\u30b0<\/li>\n<li>\u30ea\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u6e2c\u5b9a<\/li>\n<li>\u7c98\u5ea6\n<\/li>\n<li>k<sub>D<\/sub><\/li>\n<li>B<sub>22<\/sub><\/li>\n<li>G<sub>22<\/sub><\/li>\n<li>\u0394G<\/li>\n<\/ul>\n\t<p><strong>Uncle<\/strong>\u3088\u308a\u3055\u3089\u306b\u9032\u5316\u3057\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u89e3\u6790\u88c5\u7f6e <strong>Aunty<\/strong>\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u77e5\u308a\u305f\u3044\u3067\u3059\u304b<\/p>\n\t\t\t<a href=\"https:\/\/unchainedlabs.com\/jp\/Aunty\/\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t\t\u78ba\u8a8d\u3059\u308b\n\t\t\t\t\t<\/a>\n<h2>\n\t\t\u52d5\u753b\n\t<\/h2>\n\t<p>\u7a3c\u50cd\u4e2d\u306eUncle\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\t<img decoding=\"async\" src=\"https:\/\/fast.wistia.com\/embed\/medias\/lushpldyka\/swatch\" alt=\"\" aria-hidden=\"true\" onload=\"this.parentNode.style.opacity=1;\" \/>\n\t<p>&nbsp;<\/p>\n<p>Uncle\u306b\u3088\u308bADC\u306e\u7279\u6027\u8a55\u4fa1\u306b\u3064\u3044\u3066\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\t<img decoding=\"async\" src=\"https:\/\/fast.wistia.com\/embed\/medias\/f9b8jpqjtc\/swatch\" alt=\"\" aria-hidden=\"true\" onload=\"this.parentNode.style.opacity=1;\" \/>\n<h2>\n\t\t\u4e00\u56de\u306e\u6e2c\u5b9a\u3067\u591a\u304f\u306e\u30c7\u30fc\u30bf\u3092\n\t<\/h2>\n\t<p>\u65b0\u3057\u3044\u88fd\u5264\u3084\u30b3\u30f3\u30b9\u30c8\u30e9\u30af\u30c8\u3092\u6a21\u7d22\u3057\u3066\u3044\u307e\u3059\u304b\u3002\u6700\u592748\u30b5\u30f3\u30d7\u30eb\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u6e2c\u5b9a\u306b\u3088\u308a\u30012\u6642\u9593\u4ee5\u5185\u306b\u305d\u306e\u7b54\u3048\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002T<sub>m<\/sub>\u3068T<sub>agg<\/sub>\u3092\u540c\u6642\u306b\u6e2c\u5b9a\u3057\u3001\u30a2\u30f3\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u304c\u51dd\u96c6\u306b\u3064\u306a\u304c\u308b\u30bf\u30a4\u30df\u30f3\u30b0\u3092\u628a\u63e1\u3067\u304d\u307e\u3059\u3002\u307e\u305f\u3001\u6e29\u5ea6\u4e0a\u6607\u306e\u524d\u306bDLS\u6e2c\u5b9a\u5024\u3092\u8ffd\u52a0\u3059\u308b\u3053\u3068\u3067\u3001\u51dd\u96c6\u30c8\u30e9\u30d6\u30eb\u304c\u767a\u751f\u3057\u305f\u304b\u3069\u3046\u304b\u3092\u3059\u3050\u306b\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/DLS-sq2@2x.png\" alt=\"DLS-sq2@2x\" itemprop=\"image\" height=\"1161\" width=\"1340\" title=\"DLS-sq2@2x\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/07\/simmer.png\" alt=\"simmer\" itemprop=\"image\" height=\"461\" width=\"1033\" title=\"simmer\" onerror=\"this.style.display='none'\"  \/>\n<h2>\n\t\t\u7b49\u6e29\u30c7\u30fc\u30bf\n\t<\/h2>\n\t<p>\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7b49\u6e29\u5b89\u5b9a\u6027\u6e2c\u5b9a\u306b\u65e9\u671f\u6bb5\u968e\u3067\u53d6\u308a\u7d44\u3080\u3053\u3068\u3067\u3001\u9577\u671f\u4fdd\u5b58\u8a66\u9a13\u306b\u5148\u624b\u3092\u6253\u3064\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002Uncle\u306b\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u30ec\u30dd\u30fc\u30bf\u30fc\u8272\u7d20\u3001\u30d9\u30af\u30bf\u30fc\u30da\u30a4\u30ed\u30fc\u30c9\u3001\u305d\u3057\u3066\u9759\u7f6e\u6e29\u5ea6\u3067\u306e\u305d\u308c\u3089\u306e\u5909\u5316\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u3001\u30aa\u30fc\u30c0\u30fc\u30e1\u30a4\u30c9\u3055\u308c\u305f\u4e00\u9023\u306e\u30a2\u30d7\u30ea\u304c\u3042\u308a\u307e\u3059\u3002\u30ad\u30e5\u30d9\u30c3\u30c8\u306eUni\u306b\u30b5\u30f3\u30d7\u30eb\u3092\u30ed\u30fc\u30c9\u3057\u3001\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30bf\u30fc\u306b\u4fdd\u7ba1\u3059\u308c\u3070\u3001\u597d\u304d\u306a\u6642\u306bUncle\u306b\u623b\u3057\u3066\u3001\u6319\u52d5\u304c\u6b63\u5e38\u3067\u306a\u3044\u30b5\u30f3\u30d7\u30eb\u3092\u628a\u63e1\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<h2>\n\t\tAAV\u30ad\u30e3\u30d7\u30b7\u30c9\u306e\u5b89\u5b9a\u6027\n\t<\/h2>\n\t<p>Uncle\u3068SYBR Gold\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001AAV\u30ad\u30e3\u30d7\u30b7\u30c9\u5d29\u58ca\u524d\u306bDNA\u304c\u6f0f\u51fa\u3057\u59cb \u3081\u308b\u6e29\u5ea6\u3092\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u6700\u521d\u306e\u904a\u96e2DNA\u91cf\u3068\u71b1\u50be\u659c\u8a66\u9a13\u5f8c\u306b\u904a\u96e2\u3057\u305f\u91cf\u3092\u8ffd\u8de1\u3067\u304d\u307e\u3059\u3002SLS\u3068DLS\u306b\u3088\u308a\u51dd\u96c6\u304c\u5236\u5fa1\u3067\u304d\u306a\u304f\u306a\u308b\u6642\u671f\u3092\u628a\u63e1\u3057\u307e\u3059\u3002<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/capsid@2x.png\" alt=\"capsid@2x\" itemprop=\"image\" height=\"709\" width=\"832\" title=\"capsid@2x\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/07\/Jailbreaks_graph_hi_res.png\" alt=\"Jailbreaks_graph_hi_res\" itemprop=\"image\" height=\"464\" width=\"457\" title=\"Jailbreaks_graph_hi_res\" onerror=\"this.style.display='none'\"  \/>\n<h2>\n\t\t\u30b2\u30ce\u30e0\u30ea\u30fc\u30af\u306e\u7279\u5b9a\n\t<\/h2>\n\t<p>\u30d9\u30af\u30bf\u30fc\u304b\u3089DNA\u3084RNA\u304c\u9577\u671f\u9593\u306b\u308f\u305f\u3063\u3066\u6d41\u51fa\u3057\u306a\u3044\u3053\u3068\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002Uncle\u306e\u30d5\u30eb\u30b9\u30da\u30af\u30c8\u30eb\u86cd\u5149\u3068SYBR Gold\u7b49\u6e29\u5b89\u5b9a\u6027\u8a66\u9a13\u306e\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u308a\u3001\u52a0\u901f\u3055\u308c\u305f\u7b49\u6e29\u4fdd\u5b58\u30c6\u30b9\u30c8\u3092\u65e9\u671f\u306b\u5c11\u91cf\u3067\u5b9f\u65bd\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<h2>\n\t\tB<sub>22<\/sub> &#038; k<sub>D<\/sub>\n\t<\/h2>\n\t<p>B<sub>22<\/sub>\u3068k<sub>D<\/sub>\u3092\u540c\u3058\u88c5\u7f6e\u3067\u540c\u6642\u306b\u53d6\u5f97\u3067\u304d\u307e\u3059\u3002\u6dfb\u52a0\u5264\u3092\u5909\u3048\u3066\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u72b6\u614b\u3092\u3059\u3050\u306b\u78ba\u8a8d\u3067\u304d\u307e\u3059\u3002\u30bf\u30f3\u30d1\u30af\u8cea\u51e6\u65b9\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u76ee\u7684\u306b\u9069\u3057\u305f\u3082\u306e\u304b\u3001\u51dd\u96c6\u30ea\u30b9\u30af\u304c\u3042\u308b\u304b\u3001\u305d\u306e\u5834\u3067\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u9ad8\u6fc3\u5ea6\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5bfe\u3057\u3066\u306fG<sub>22<\/sub>\u304c\u5229\u7528\u3067\u304d\u307e\u3059\u3002<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/B22-new-legend-4@2x.png\" alt=\"B22-new-legend-4@2x\" itemprop=\"image\" height=\"852\" width=\"920\" title=\"B22-new-legend-4@2x\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/UNI@2x.png\" alt=\"UNI@2x\" itemprop=\"image\" height=\"778\" width=\"832\" title=\"UNI@2x\" onerror=\"this.style.display='none'\"  \/>\n<h2>\n\t\t\u5c11\u91cf\u30b5\u30f3\u30d7\u30eb\n\t<\/h2>\n\t<p>Uncle\u306f\u3001\u3088\u308a\u5c11\u306a\u3044\u30b5\u30f3\u30d7\u30eb\u3067\u3088\u308a\u591a\u304f\u306e\u30c7\u30fc\u30bf\u3092\u53d6\u5f97\u3067\u304d\u307e\u3059\u3002\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u91cf\u306f\u305f\u3063\u305f\u306e9\u03bcL\u3067\u3001\u67d4\u8edf\u306a\u5bfe\u5fdc\u304c\u53ef\u80fd\u3067\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u5348\u524d\u4e2d\u306b1\u30b5\u30f3\u30d7\u30eb\u3001\u5348\u5f8c\u306b48\u30b5\u30f3\u30d7\u30eb\u3002\u5fc5\u8981\u306b\u5fdc\u3058\u3001DLS\u3082\u8aad\u307f\u53d6\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u307e\u305f\u306f\u3001DLS\u3092\u30c1\u30a7\u30c3\u30af\u3057\u3066\u304b\u30893\u65e5\u9593\u306e\u5b9f\u9a13\u3092\u958b\u59cb\u3057\u3066\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u5b89\u5b9a\u6027\u3092\u30e2\u30cb\u30bf\u30fc\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30b5\u30f3\u30d7\u30eb\u306f\u6c17\u5bc6\u306b\u5bc6\u5c01\u3055\u308c\u308b\u306e\u3067\u3001\u77ed\u6642\u9593\u3067\u3082\u9577\u6642\u9593\u3067\u3082\u554f\u984c\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<h2>\n\t\t\u30d5\u30eb\u30b9\u30da\u30af\u30c8\u30e9\u30e0\n\t<\/h2>\n\t<p>\u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u3084\u907a\u4f1d\u5b50\u30d9\u30af\u30bf\u30fc\u306f\u7279\u5225\u3067\u3059\u3002Uncle\u3067\u5168\u86cd\u5149\u30b9\u30da\u30af\u30c8\u30eb\u304c\u5f97\u3089\u308c\u308b\u306e\u3067\u3001\u30b5\u30f3\u30d7\u30eb\u306e\u6319\u52d5\u3092\u4e8b\u524d\u306b\u77e5\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u8272\u7d20\u3092\u4f7f\u3063\u3066\u65b0\u3057\u3044\u767a\u60f3\u3092\u8a66\u3057\u305f\u3044\u5834\u5408\u306b\u3082\u3001Uncle\u306f\u5bfe\u5fdc\u3067\u304d\u307e\u3059\u3002Uncle\u306eSLS\u306f\u30012\u3064\u306e\u6ce2\u9577\u3067\u51dd\u96c6\u3092\u6355\u6349\u3059\u308b\u305f\u3081\u3001\u8d85\u9ad8\u611f\u5ea6\u3067\u3001\u5e45\u5e83\u3044\u30b5\u30a4\u30ba\u306e\u51dd\u96c6\u3092\u767a\u898b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/full-spectrum@2x.png\" alt=\"full-spectrum@2x\" itemprop=\"image\" height=\"907\" width=\"920\" title=\"full-spectrum@2x\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/Analysis-red-integrity-expt-list-2@2x.png\" alt=\"Analysis-red-integrity-expt-list-2@2x\" itemprop=\"image\" height=\"619\" width=\"1540\" title=\"Analysis-red-integrity-expt-list-2@2x\" onerror=\"this.style.display='none'\"  \/>\n<h2>\n\t\t21CFRp11\n\t<\/h2>\n\t<p>\u30e9\u30dc\u306e\u3042\u308b\u5730\u57df\u306b\u3088\u3063\u3066\u306f\u3001\u30c7\u30fc\u30bf\u3078\u306e\u30a2\u30af\u30bb\u30b9\u3092\u5236\u5fa1\u3057\u3001\u305d\u306e\u5b8c\u5168\u6027\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u304c\u5fc5\u9808\u3067\u3059\u3002Uncle\u3067\u306f\u300121CFRp11\u306b\u6e96\u62e0\u3057\u305f\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u30c4\u30fc\u30eb\u304c\u63d0\u4f9b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h2>\n\t\t\u95a2\u9023\u8cc7\u6599\n\t<\/h2>\n<h2>\n\t\tWebinars\n\t<\/h2>\n\t<a href=\"https:\/\/unchainedlabs.wistia.com\/medias\/idt5olnwxw\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.wistia.com\/medias\/idt5olnwxw\"><\/a>\n\t\t\tBeef up your protein formulation toolbox with Uncle\t\t\t\n\t\t\t\t<p>Kevin Lance, PhD, Marketing Manager, Analytical Instruments, Unchained Labs<\/p>\n\t<a href=\"https:\/\/unchainedlabs.wistia.com\/medias\/mc9fqzq2o5\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.wistia.com\/medias\/mc9fqzq2o5\"><\/a>\n\t\t\tSee when your AAV hits the eject button with Uncle\t\t\t\n\t\t\t\t<p>Kevin Lance, PhD, Marketing Manager, Unchained Labs<\/p>\n\t<a href=\"https:\/\/www.workcast.com\/ControlUsher.aspx?cpak=5951679521688832&#038;pak=6652414520182051\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/www.workcast.com\/ControlUsher.aspx?cpak=5951679521688832&#038;pak=6652414520182051\"><\/a>\n\t\t\tImproving antibody drug candidate success through developability assessments\t\t\t\n\t\t\t\t<p>Jacek Ostrowski, PhD, Associate Director, Protein Chemistry, AlivaMab Discovery Services<br \/>Kevin Lance, PhD, Marketing Manager, Analytical Instruments, Unchained Labs<\/p>\n\t<a href=\"http:\/\/www.healthtech.com\/unchained-thermal-unfolding-and-aggregation-analysis\/\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to http:\/\/www.healthtech.com\/unchained-thermal-unfolding-and-aggregation-analysis\/\"><\/a>\n\t\t\tThermal unfolding and aggregation analysis of lead antibodies and variants derived from synthetic antibody libraries\t\t\t\n\t\t\t\t<p>Aaron K. Sato, Ph.D., CSO Biopharma, Twist Biopharma, a division of Twist Bioscience<br \/>Kevin Lance, Ph.D., Marketing Manager, Unchained Labs<\/p>\n<h2>\n\t\tApp Notes\n\t<\/h2>\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/06\/App_Note_Uncle_Uncle-stays-hot-for-proteins_RevA_r2.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/06\/App_Note_Uncle_Uncle-stays-hot-for-proteins_RevA_r2.pdf\"><\/a>\n\t\t\tUncle stays hot for proteins with isothermal apps\t\t\t\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2023\/04\/Meet_our_UNcle_Tech_Note_revE_r3.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2023\/04\/Meet_our_UNcle_Tech_Note_revE_r3.pdf\"><\/a>\n\t\t\tMeet our Uncle: 12 stability applications on one platform\t\t\t\n\t<a href=\"\/wp-content\/uploads\/2021\/11\/DNA-leaks-before-capsids-pop-AAV-thermal-stability-on-Uncle.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to \/wp-content\/uploads\/2021\/11\/DNA-leaks-before-capsids-pop-AAV-thermal-stability-on-Uncle.pdf\"><\/a>\n\t\t\tDNA leaks before capsids pop: AAV thermal stability on Uncle\t\t\t\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/sizing-with-thermal-ramp\/\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/sizing-with-thermal-ramp\/\"><\/a>\n\t\t\tSize matters in Uncle&#8217;s Sizing with Thermal Ramp app\t\t\t\n\t<a href=\"\/wp-content\/uploads\/2021\/11\/AN-See-it-all-with-Uncles-full-spectrum-analysis.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to \/wp-content\/uploads\/2021\/11\/AN-See-it-all-with-Uncles-full-spectrum-analysis.pdf\"><\/a>\n\t\t\tSee it all with Uncle&#8217;s full-spectrum analysis\t\t\t\n\t<a href=\"\/wp-content\/uploads\/2021\/11\/AN_Assess_aggregation_risk_at_higher_protein_concentrations_with_G22.pdf\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to \/wp-content\/uploads\/2021\/11\/AN_Assess_aggregation_risk_at_higher_protein_concentrations_with_G22.pdf\"><\/a>\n\t\t\tAssess aggregation risk at higher protein concentrations with G<sub>22<\/sub>\t\t\t\n<h2>\n\t\tTechnology\n\t<\/h2>\n\t<a href=\"\/differential-scanning-fluorimetry\/\" target=\"_self\"  aria-label=\"Go to \/differential-scanning-fluorimetry\/\"><\/a>\n\t\t\tDifferential Scanning Fluorimetry (DSF)\t\t\t\n\t<a href=\"\/static-light-scattering\/\" target=\"_self\"  aria-label=\"Go to \/static-light-scattering\/\"><\/a>\n\t\t\tStatic Light Scattering (SLS)\t\t\t\n\t<a href=\"\/dynamic-light-scattering\/\" target=\"_self\"  aria-label=\"Go to \/dynamic-light-scattering\/\"><\/a>\n\t\t\tDynamic Light Scattering (DLS)\t\t\t\n<h2>\n\t\tSoftware\n\t<\/h2>\n\t<a href=\"https:\/\/go.unchainedlabs.com\/l\/907652\/2021-02-17\/9tv6\" target=\"_blank\" rel=\"noopener\" aria-label=\"Go to https:\/\/go.unchainedlabs.com\/l\/907652\/2021-02-17\/9tv6\"><\/a>\n\t\t\tDownload Uncle Software\t\t\t\n<h2>\n\t\t\u304a\u898b\u7a4d\u308a\u30fb\u30c7\u30e2\u306e\u4f9d\u983c\n\t<\/h2>\n\t\t\t<a href=\"https:\/\/go.unchainedlabs.com\/RequestQuoteDemoJapan%20\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t\t\u4f9d\u983c\u3059\u308b\n\t\t\t\t\t<\/a>\n<h2>\n\t\t\u95a2\u9023\u88fd\u54c1\n\t<\/h2>\n\t<a href=\"https:\/\/unchainedlabs.com\/jp\/stunner\/\" target=\"_self\"  aria-label=\"Go to https:\/\/unchainedlabs.com\/jp\/stunner\/\"><\/a>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/02\/Stunner_Uncle-product-page_3-e1658951180154.png\" alt=\"Stunner_Uncle-product-page_3\" title=\"Stunner_Uncle-product-page_3\" itemprop=\"image\"\/>\n\t\t<h3>Stunner<\/h3>\t\t\t\n\t\t\t\t<p>\u5b9a\u91cf\u30fb\u30b5\u30a4\u30b8\u30f3\u30b0\u88c5\u7f6e<\/p>\n\t<a href=\"\/jp\/big-tuna\/\" target=\"_self\"  aria-label=\"Go to \/jp\/big-tuna\/\"><\/a>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/Big-Tuna-fron@2xt.png\" alt=\"Big-Tuna-fron@2xt\" title=\"Big-Tuna-fron@2xt\" itemprop=\"image\"\/>\n\t\t<h3>Big Tuna<\/h3>\t\t\t\n\t\t\t\t<p>\u30d7\u30ec\u30fc\u30c8\u30d9\u30fc\u30b9\u30d0\u30c3\u30d5\u30a1\u30fc\u4ea4\u63db\u88c5\u7f6e<\/p>\n\n","protected":false},"excerpt":{"rendered":"<p>Uncle \u30aa\u30fc\u30eb\u30a4\u30f3\u30ef\u30f3 \u5b89\u5b9a\u6027\u8a55\u4fa1\u88c5\u7f6e \u30ab\u30bf\u30ed\u30b0 \u6982\u8981 \u52d5\u753b \u6a5f\u80fd \u95a2\u9023\u8cc7\u6599 \u30ef\u30f3\u30b9\u30c8\u30c3\u30d7\u306e\u5b89\u5b9a\u6027\u8a55\u4fa1 \u5927\u91cf\u306e\u30b5\u30f3\u30d7\u30eb\u3092\u5fc5\u8981\u3068\u3059\u308b\u30c4\u30fc\u30eb\u3092\u8907\u6570\u7528\u3044\u3066\u5b89\u5b9a\u6027\u3092\u8a55\u4fa1\u3059\u308b\u306b\u306f\u81a8\u5927\u306a\u52b4\u529b\u304c\u5fc5\u8981\u3067\u3059\u3002Uncle\u306f\u86cd\u5149\u3001SLS\u3001DLS\u3068\u3044\u30463\u3064\u306e\u7570\u306a\u308b\u6e2c\u5b9a\u30e2\u30fc\u30c9\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u3044\u307e\u3059\u306e\u3067\u3001\u308f\u305a\u304b\u6570\u6642\u9593\u3067\u3059\u3079\u3066\u306e\u30c7\u30fc\u30bf\u3092\u53d6\u5f97\u3057\u3001\u4f7f\u7528\u3059\u308b\u30b5\u30f3\u30d7\u30eb\u306e\u91cf\u3092\u5927\u5e45\u306b\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u5f97\u3089\u308c\u305f\u3059\u3079\u3066\u306e\u60c5\u5831\u3092\u7528\u3044\u3066\u3001\u6700\u9069\u306a\u51e6\u65b9\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u307e\u305f\u306f\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3092\u7c21\u5358\u306b\u9078\u629e\u3067\u304d\u307e\u3059\u3002\u30ab\u30bf\u30ed\u30b0\u306f\u3053\u3061\u3089\u3002 Tm &amp; T agg \u7b49\u6e29\u5b89\u5b9a\u6027 \u30a6\u30a4\u30eb\u30b9\u30ab\u30d7\u30b7\u30c9\u306e\u5b89\u5b9a\u6027 SYPRO\u3092\u7528\u3044\u305fTm\uff08DSF\uff09 \u30b5\u30a4\u30b8\u30f3\u30b0\u3068\u591a\u5206\u6563\u6027 \u30b5\u30fc\u30de\u30eb\u30e9\u30f3\u30d7\u306b\u3088\u308b\u30b5\u30a4\u30b8\u30f3\u30b0 \u30ea\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u6e2c\u5b9a \u7c98\u5ea6 kD B22 G22 \u0394G Uncle\u3088\u308a\u3055\u3089\u306b\u9032\u5316\u3057\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u89e3\u6790\u88c5\u7f6e Aunty\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u77e5\u308a\u305f\u3044\u3067\u3059\u304b \u78ba\u8a8d\u3059\u308b \u52d5\u753b \u7a3c\u50cd\u4e2d\u306eUncle\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002 &nbsp; Uncle\u306b\u3088\u308bADC\u306e\u7279\u6027\u8a55\u4fa1\u306b\u3064\u3044\u3066\u3054\u89a7\u304f\u3060\u3055\u3044\u3002 \u4e00\u56de\u306e\u6e2c\u5b9a\u3067\u591a\u304f\u306e\u30c7\u30fc\u30bf\u3092 \u65b0\u3057\u3044\u88fd\u5264\u3084\u30b3\u30f3\u30b9\u30c8\u30e9\u30af\u30c8\u3092\u6a21\u7d22\u3057\u3066\u3044\u307e\u3059\u304b\u3002\u6700\u592748\u30b5\u30f3\u30d7\u30eb\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u6e2c\u5b9a\u306b\u3088\u308a\u30012\u6642\u9593\u4ee5\u5185\u306b\u305d\u306e\u7b54\u3048\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002Tm\u3068Tagg\u3092\u540c\u6642\u306b\u6e2c\u5b9a\u3057\u3001\u30a2\u30f3\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u304c\u51dd\u96c6\u306b\u3064\u306a\u304c\u308b\u30bf\u30a4\u30df\u30f3\u30b0\u3092\u628a\u63e1\u3067\u304d\u307e\u3059\u3002\u307e\u305f\u3001\u6e29\u5ea6\u4e0a\u6607\u306e\u524d\u306bDLS\u6e2c\u5b9a\u5024\u3092\u8ffd\u52a0\u3059\u308b\u3053\u3068\u3067\u3001\u51dd\u96c6\u30c8\u30e9\u30d6\u30eb\u304c\u767a\u751f\u3057\u305f\u304b\u3069\u3046\u304b\u3092\u3059\u3050\u306b\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 \u7b49\u6e29\u30c7\u30fc\u30bf \u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7b49\u6e29\u5b89\u5b9a\u6027\u6e2c\u5b9a\u306b\u65e9\u671f\u6bb5\u968e\u3067\u53d6\u308a\u7d44\u3080\u3053\u3068\u3067\u3001\u9577\u671f\u4fdd\u5b58\u8a66\u9a13\u306b\u5148\u624b\u3092\u6253\u3064\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002Uncle\u306b\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u30ec\u30dd\u30fc\u30bf\u30fc\u8272\u7d20\u3001\u30d9\u30af\u30bf\u30fc\u30da\u30a4\u30ed\u30fc\u30c9\u3001\u305d\u3057\u3066\u9759\u7f6e\u6e29\u5ea6\u3067\u306e\u305d\u308c\u3089\u306e\u5909\u5316\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u3001\u30aa\u30fc\u30c0\u30fc\u30e1\u30a4\u30c9\u3055\u308c\u305f\u4e00\u9023\u306e\u30a2\u30d7\u30ea\u304c\u3042\u308a\u307e\u3059\u3002\u30ad\u30e5\u30d9\u30c3\u30c8\u306eUni\u306b\u30b5\u30f3\u30d7\u30eb\u3092\u30ed\u30fc\u30c9\u3057\u3001\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30bf\u30fc\u306b\u4fdd\u7ba1\u3059\u308c\u3070\u3001\u597d\u304d\u306a\u6642\u306bUncle\u306b\u623b\u3057\u3066\u3001\u6319\u52d5\u304c\u6b63\u5e38\u3067\u306a\u3044\u30b5\u30f3\u30d7\u30eb\u3092\u628a\u63e1\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 AAV\u30ad\u30e3\u30d7\u30b7\u30c9\u306e\u5b89\u5b9a\u6027 Uncle\u3068SYBR Gold\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001AAV\u30ad\u30e3\u30d7\u30b7\u30c9\u5d29\u58ca\u524d\u306bDNA\u304c\u6f0f\u51fa\u3057\u59cb \u3081\u308b\u6e29\u5ea6\u3092\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u6700\u521d\u306e\u904a\u96e2DNA\u91cf\u3068\u71b1\u50be\u659c\u8a66\u9a13\u5f8c\u306b\u904a\u96e2\u3057\u305f\u91cf\u3092\u8ffd\u8de1\u3067\u304d\u307e\u3059\u3002SLS\u3068DLS\u306b\u3088\u308a\u51dd\u96c6\u304c\u5236\u5fa1\u3067\u304d\u306a\u304f\u306a\u308b\u6642\u671f\u3092\u628a\u63e1\u3057\u307e\u3059\u3002 \u30b2\u30ce\u30e0\u30ea\u30fc\u30af\u306e\u7279\u5b9a \u30d9\u30af\u30bf\u30fc\u304b\u3089DNA\u3084RNA\u304c\u9577\u671f\u9593\u306b\u308f\u305f\u3063\u3066\u6d41\u51fa\u3057\u306a\u3044\u3053\u3068\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002Uncle\u306e\u30d5\u30eb\u30b9\u30da\u30af\u30c8\u30eb\u86cd\u5149\u3068SYBR Gold\u7b49\u6e29\u5b89\u5b9a\u6027\u8a66\u9a13\u306e\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u308a\u3001\u52a0\u901f\u3055\u308c\u305f\u7b49\u6e29\u4fdd\u5b58\u30c6\u30b9\u30c8\u3092\u65e9\u671f\u306b\u5c11\u91cf\u3067\u5b9f\u65bd\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 B22 &#038; kD B22\u3068kD\u3092\u540c\u3058\u88c5\u7f6e\u3067\u540c\u6642\u306b\u53d6\u5f97\u3067\u304d\u307e\u3059\u3002\u6dfb\u52a0\u5264\u3092\u5909\u3048\u3066\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u72b6\u614b\u3092\u3059\u3050\u306b\u78ba\u8a8d\u3067\u304d\u307e\u3059\u3002\u30bf\u30f3\u30d1\u30af\u8cea\u51e6\u65b9\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u76ee\u7684\u306b\u9069\u3057\u305f\u3082\u306e\u304b\u3001\u51dd\u96c6\u30ea\u30b9\u30af\u304c\u3042\u308b\u304b\u3001\u305d\u306e\u5834\u3067\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u9ad8\u6fc3\u5ea6\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5bfe\u3057\u3066\u306fG22\u304c\u5229\u7528\u3067\u304d\u307e\u3059\u3002 \u5c11\u91cf\u30b5\u30f3\u30d7\u30eb Uncle\u306f\u3001\u3088\u308a\u5c11\u306a\u3044\u30b5\u30f3\u30d7\u30eb\u3067\u3088\u308a\u591a\u304f\u306e\u30c7\u30fc\u30bf\u3092\u53d6\u5f97\u3067\u304d\u307e\u3059\u3002\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u91cf\u306f\u305f\u3063\u305f\u306e9\u03bcL\u3067\u3001\u67d4\u8edf\u306a\u5bfe\u5fdc\u304c\u53ef\u80fd\u3067\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u5348\u524d\u4e2d\u306b1\u30b5\u30f3\u30d7\u30eb\u3001\u5348\u5f8c\u306b48\u30b5\u30f3\u30d7\u30eb\u3002\u5fc5\u8981\u306b\u5fdc\u3058\u3001DLS\u3082\u8aad\u307f\u53d6\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u307e\u305f\u306f\u3001DLS\u3092\u30c1\u30a7\u30c3\u30af\u3057\u3066\u304b\u30893\u65e5\u9593\u306e\u5b9f\u9a13\u3092\u958b\u59cb\u3057\u3066\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u5b89\u5b9a\u6027\u3092\u30e2\u30cb\u30bf\u30fc\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30b5\u30f3\u30d7\u30eb\u306f\u6c17\u5bc6\u306b\u5bc6\u5c01\u3055\u308c\u308b\u306e\u3067\u3001\u77ed\u6642\u9593\u3067\u3082\u9577\u6642\u9593\u3067\u3082\u554f\u984c\u306f\u3042\u308a\u307e\u305b\u3093\u3002 \u30d5\u30eb\u30b9\u30da\u30af\u30c8\u30e9\u30e0 \u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u3084\u907a\u4f1d\u5b50\u30d9\u30af\u30bf\u30fc\u306f\u7279\u5225\u3067\u3059\u3002Uncle\u3067\u5168\u86cd\u5149\u30b9\u30da\u30af\u30c8\u30eb\u304c\u5f97\u3089\u308c\u308b\u306e\u3067\u3001\u30b5\u30f3\u30d7\u30eb\u306e\u6319\u52d5\u3092\u4e8b\u524d\u306b\u77e5\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u8272\u7d20\u3092\u4f7f\u3063\u3066\u65b0\u3057\u3044\u767a\u60f3\u3092\u8a66\u3057\u305f\u3044\u5834\u5408\u306b\u3082\u3001Uncle\u306f\u5bfe\u5fdc\u3067\u304d\u307e\u3059\u3002Uncle\u306eSLS\u306f\u30012\u3064\u306e\u6ce2\u9577\u3067\u51dd\u96c6\u3092\u6355\u6349\u3059\u308b\u305f\u3081\u3001\u8d85\u9ad8\u611f\u5ea6\u3067\u3001\u5e45\u5e83\u3044\u30b5\u30a4\u30ba\u306e\u51dd\u96c6\u3092\u767a\u898b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 21CFRp11 \u30e9\u30dc\u306e\u3042\u308b\u5730\u57df\u306b\u3088\u3063\u3066\u306f\u3001\u30c7\u30fc\u30bf\u3078\u306e\u30a2\u30af\u30bb\u30b9\u3092\u5236\u5fa1\u3057\u3001\u305d\u306e\u5b8c\u5168\u6027\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u304c\u5fc5\u9808\u3067\u3059\u3002Uncle\u3067\u306f\u300121CFRp11\u306b\u6e96\u62e0\u3057\u305f\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u30c4\u30fc\u30eb\u304c\u63d0\u4f9b\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u95a2\u9023\u8cc7\u6599 Webinars&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-4403","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0Uncle | Unchained Labs<\/title>\n<meta name=\"description\" content=\"Uncle\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b89\u5b9a\u6027\u3092\u3001\u86cd\u5149\u3001SLS\u3001DLS\u306e3\u3064\u306e\u30e2\u30fc\u30c9\u3067\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3088\u308a\u5c11\u91cf\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u6570\u6642\u9593\u3067\u5168\u3066\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unchainedlabs.com\/jp\/uncle\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0Uncle | Unchained Labs\" \/>\n<meta property=\"og:description\" content=\"Uncle\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b89\u5b9a\u6027\u3092\u3001\u86cd\u5149\u3001SLS\u3001DLS\u306e3\u3064\u306e\u30e2\u30fc\u30c9\u3067\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3088\u308a\u5c11\u91cf\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u6570\u6642\u9593\u3067\u5168\u3066\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\" \/>\n<meta property=\"og:url\" content=\"https:\/\/unchainedlabs.com\/jp\/uncle\/\" \/>\n<meta property=\"og:site_name\" content=\"unchainedlabs\" \/>\n<meta property=\"article:modified_time\" content=\"2025-01-21T02:38:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/UNcle-front-transparent_2.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/\",\"url\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/\",\"name\":\"\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0Uncle | Unchained Labs\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/wp-content\\\/uploads\\\/2021\\\/12\\\/UNcle-front-transparent_2.png\",\"datePublished\":\"2021-12-07T04:53:39+00:00\",\"dateModified\":\"2025-01-21T02:38:30+00:00\",\"description\":\"Uncle\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b89\u5b9a\u6027\u3092\u3001\u86cd\u5149\u3001SLS\u3001DLS\u306e3\u3064\u306e\u30e2\u30fc\u30c9\u3067\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3088\u308a\u5c11\u91cf\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u6570\u6642\u9593\u3067\u5168\u3066\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/#primaryimage\",\"url\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/wp-content\\\/uploads\\\/2021\\\/12\\\/UNcle-front-transparent_2.png\",\"contentUrl\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/wp-content\\\/uploads\\\/2021\\\/12\\\/UNcle-front-transparent_2.png\",\"width\":740,\"height\":678},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/uncle\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Uncle\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/#website\",\"url\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/\",\"name\":\"unchainedlabs\",\"description\":\"Just another WordPress site\",\"publisher\":{\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/#organization\",\"name\":\"Unchained Labs\",\"url\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/unchainedlabs.com\\\/wp-content\\\/uploads\\\/2021\\\/10\\\/g-logo.svg\",\"contentUrl\":\"https:\\\/\\\/unchainedlabs.com\\\/wp-content\\\/uploads\\\/2021\\\/10\\\/g-logo.svg\",\"width\":192,\"height\":41,\"caption\":\"Unchained Labs\"},\"image\":{\"@id\":\"https:\\\/\\\/unchainedlabs.com\\\/jp\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0Uncle | Unchained Labs","description":"Uncle\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b89\u5b9a\u6027\u3092\u3001\u86cd\u5149\u3001SLS\u3001DLS\u306e3\u3064\u306e\u30e2\u30fc\u30c9\u3067\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3088\u308a\u5c11\u91cf\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u6570\u6642\u9593\u3067\u5168\u3066\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/unchainedlabs.com\/jp\/uncle\/","og_locale":"en_US","og_type":"article","og_title":"\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0Uncle | Unchained Labs","og_description":"Uncle\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b89\u5b9a\u6027\u3092\u3001\u86cd\u5149\u3001SLS\u3001DLS\u306e3\u3064\u306e\u30e2\u30fc\u30c9\u3067\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3088\u308a\u5c11\u91cf\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u6570\u6642\u9593\u3067\u5168\u3066\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002","og_url":"https:\/\/unchainedlabs.com\/jp\/uncle\/","og_site_name":"unchainedlabs","article_modified_time":"2025-01-21T02:38:30+00:00","og_image":[{"url":"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/UNcle-front-transparent_2.png","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/unchainedlabs.com\/jp\/uncle\/","url":"https:\/\/unchainedlabs.com\/jp\/uncle\/","name":"\u30bf\u30f3\u30d1\u30af\u8cea\u5b89\u5b9a\u6027\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0Uncle | Unchained Labs","isPartOf":{"@id":"https:\/\/unchainedlabs.com\/jp\/#website"},"primaryImageOfPage":{"@id":"https:\/\/unchainedlabs.com\/jp\/uncle\/#primaryimage"},"image":{"@id":"https:\/\/unchainedlabs.com\/jp\/uncle\/#primaryimage"},"thumbnailUrl":"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/UNcle-front-transparent_2.png","datePublished":"2021-12-07T04:53:39+00:00","dateModified":"2025-01-21T02:38:30+00:00","description":"Uncle\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b89\u5b9a\u6027\u3092\u3001\u86cd\u5149\u3001SLS\u3001DLS\u306e3\u3064\u306e\u30e2\u30fc\u30c9\u3067\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3088\u308a\u5c11\u91cf\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u6570\u6642\u9593\u3067\u5168\u3066\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002","breadcrumb":{"@id":"https:\/\/unchainedlabs.com\/jp\/uncle\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/unchainedlabs.com\/jp\/uncle\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/unchainedlabs.com\/jp\/uncle\/#primaryimage","url":"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/UNcle-front-transparent_2.png","contentUrl":"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/UNcle-front-transparent_2.png","width":740,"height":678},{"@type":"BreadcrumbList","@id":"https:\/\/unchainedlabs.com\/jp\/uncle\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/unchainedlabs.com\/jp\/"},{"@type":"ListItem","position":2,"name":"Uncle"}]},{"@type":"WebSite","@id":"https:\/\/unchainedlabs.com\/jp\/#website","url":"https:\/\/unchainedlabs.com\/jp\/","name":"unchainedlabs","description":"Just another WordPress site","publisher":{"@id":"https:\/\/unchainedlabs.com\/jp\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/unchainedlabs.com\/jp\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/unchainedlabs.com\/jp\/#organization","name":"Unchained Labs","url":"https:\/\/unchainedlabs.com\/jp\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/unchainedlabs.com\/jp\/#\/schema\/logo\/image\/","url":"https:\/\/unchainedlabs.com\/wp-content\/uploads\/2021\/10\/g-logo.svg","contentUrl":"https:\/\/unchainedlabs.com\/wp-content\/uploads\/2021\/10\/g-logo.svg","width":192,"height":41,"caption":"Unchained Labs"},"image":{"@id":"https:\/\/unchainedlabs.com\/jp\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/pages\/4403","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/comments?post=4403"}],"version-history":[{"count":3,"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/pages\/4403\/revisions"}],"predecessor-version":[{"id":17822,"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/pages\/4403\/revisions\/17822"}],"wp:attachment":[{"href":"https:\/\/unchainedlabs.com\/jp\/wp-json\/wp\/v2\/media?parent=4403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}