{"id":4486,"date":"2021-12-07T05:56:18","date_gmt":"2021-12-07T05:56:18","guid":{"rendered":"http:\/\/unchainedlabs.sheldon.com\/?page_id=4486"},"modified":"2025-01-23T20:06:24","modified_gmt":"2025-01-23T20:06:24","slug":"laser-induced-spectroscopy-libs","status":"publish","type":"page","link":"https:\/\/unchainedlabs.com\/jp\/laser-induced-spectroscopy-libs\/","title":{"rendered":"Laser Induced Spectroscopy (LIBS)"},"content":{"rendered":"\n<h1>\n\t\tLaser Induced Breakdown Spectroscopy\n\t<\/h1>\n\t<p>ID inorganic and metal particles with LIBS analysis<\/p>\n\t<ul>\n<li><a href=\"#tech\">Tech<\/a><\/li>\n<li><a href=\"#hound\">Hound<\/a><\/li>\n<\/ul>\n<h5>\n\t\tBlast through particle identification \n\t<\/h5>\n\t<p>When developing and manufacturing biopharmaceutical products, the presence of visible and subvisible particulate matter can delay packaging and delivery, derailing critical timelines. These particulates can include metals, fibers, glass, and other inorganic materials from processing equipment and primary packaging. Identifying the chemical composition of the particulates can help you find the source of the contamination and get your timelines back on track.<\/p>\n<p>Laser induced breakdown spectroscopy (LIBS) can help you quickly identify the chemical composition of inorganic contaminants for timely and effective contaminant elimination.<\/p>\n<h5>\n\t\tWhy laser induced breakdown spectroscopy instead of SEM-EDS?\n\t<\/h5>\n\t<p>If you just want a quick answer on why you should use LIBS instead of scanning electron microscopy &#8211; energy dispersive X-ray spectroscopy (SEM-EDS) for biopharma particle analysis, it&#8217;s because LIBS is:<\/p>\n<ul>\n<li>Easier to use, no specialist needed<\/li>\n<li>Faster, 1 sec per measurement<\/li>\n<li>Simpler, sample prep is less involved<\/li>\n<li>More informative, analyze layers, not just the surface<\/li>\n<\/ul>\n<h5>\n\t\tGet the lowdown on laser induced breakdown spectroscopy\n\t<\/h5>\n\t<p>LIBS works just as the name suggests &#8211; a laser induces the breakdown of the target material which is then analyzed spectroscopically. Here&#8217;s a closer look at what that means:<\/p>\n<h5>\n\t\tBurn through the dirt\n\t<\/h5>\n\tA laser focused on the surface of the target particle converts a small volume of the material into plasma which contains free electrons.<br \/>\n\nBecause the laser ablates the top-most surface, you can analyze multiple layers of the target material by keeping the laser focused on the same point.<br \/>\n\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/01\/Surface-ablated_no-background_r2.png\" alt=\"Surface ablated_no background_r2\" itemprop=\"image\" height=\"166\" width=\"369\" title=\"Surface ablated_no background_r2\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/01\/ID-multiple-layers_r2.png\" alt=\"ID multiple layers_r2\" itemprop=\"image\" height=\"988\" width=\"2560\" title=\"ID multiple layers_r2\" onerror=\"this.style.display='none'\"  \/>\n<h5>\n\t\tLet the electrons relax\n\t<\/h5>\n\t<p>As the plasma cools, the electrons relax back into their ground state orbitals, emitting first broad spectrum light and then discrete wavelengths that are characteristic of their atomic composition.<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/Let-the-electrons-relax_r3.png\" alt=\"Let the electrons relax_r3\" itemprop=\"image\" height=\"1235\" width=\"2560\" title=\"Let the electrons relax_r3\" onerror=\"this.style.display='none'\"  \/>\n<h5>\n\t\tMeasure atomic emissions\n\t<\/h5>\n\t<p>A detector measures the intensity of emitted light across the spectrum of wavelengths.<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/01\/Measure-atomic-emissions_r4.png\" alt=\"Measure atomic emissions_r4\" itemprop=\"image\" height=\"1236\" width=\"2196\" title=\"Measure atomic emissions_r4\" onerror=\"this.style.display='none'\"  \/>\n<h5>\n\t\tMatch spectra to references\n\t<\/h5>\n\t<p>Find the identity of the target particle by matching the LIBS spectra to a database of known spectra. <\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2022\/01\/Match-spectra-references_r6-1.png\" alt=\"Match spectra references_r6\" itemprop=\"image\" height=\"1267\" width=\"2249\" title=\"Match spectra references_r6\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2021\/12\/Hound_front_open_transparent_shadow-1.jpg\" alt=\"Hound_front_open_transparent_shadow\" title=\"Hound_front_open_transparent_shadow\" itemprop=\"image\"\/>\n\t\t\t<h3>Hound<\/h3>\t\t\t\n\t\t\t\t<p>Combining automated microscopy, Raman spectroscopy, and laser induced breakdown spectroscopy (LIBS) in a single instrument, Hound enables manual and automated identification of visible and subvisible particles across a wide range of chemical compositions using in-built and customizable reference spectra.\u00a0Count, size, and ID particles by their chemical or elemental fingerprints, all with a single easy-to-use instrument.<\/p>\n\t\t\t<a href=\"\/hound\/\" title=\"Click Here\" target=\"_self\"   role=\"button\" aria-label=\"Meet Hound\">\n\t\t\t\t\t\t\tMeet Hound\n\t\t<\/a>\n<h3>\n\t\tReady for more?\n\t<\/h3>\n\t<p>Biopharma scientists can now use the right tool for particle analysis and identification challenges with an instrument that combines laser induced breakdown spectroscopy, Raman spectroscopy, and light microscopy. Have a question or ready to find out more?<\/p>\n\t\t\t<a href=\"\/contact-us\/\" target=\"_self\">\n\t\t\t\t\t\t\tGet In touch\n\t\t\t\t\t<\/a>\n\n","protected":false},"excerpt":{"rendered":"<p>Laser Induced Breakdown Spectroscopy ID inorganic and metal particles with LIBS analysis Tech Hound Blast through particle identification When developing and manufacturing biopharmaceutical products, the presence of visible and subvisible particulate matter can delay packaging and delivery, derailing critical timelines. These particulates can include metals, fibers, glass, and other inorganic materials from processing equipment and&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-4486","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Laser Induced Breakdown Spectroscopy | Unchained Labs<\/title>\n<meta name=\"description\" content=\"Learn how Laser Induced Breakdown Spectroscopy (LIBS) can help you identify unwanted metal contaminants by their elemental composition.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unchainedlabs.com\/jp\/laser-induced-spectroscopy-libs\/\" 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