{"id":14504,"date":"2023-10-03T03:11:56","date_gmt":"2023-10-03T03:11:56","guid":{"rendered":"https:\/\/unchainedlabs.com\/jp\/?p=14504"},"modified":"2023-10-05T07:28:39","modified_gmt":"2023-10-05T07:28:39","slug":"unchained-labs-makes-waves-in-lnp-formulation-launches-the-sunny-suite","status":"publish","type":"post","link":"https:\/\/unchainedlabs.com\/jp\/unchained-labs-makes-waves-in-lnp-formulation-launches-the-sunny-suite\/","title":{"rendered":"Unchained Labs makes waves in LNP formulation, launches the Sunny Suite!"},"content":{"rendered":"

October 3, 2023 \u2013 Pleasanton, CA \u2013 Unchained Labs<\/a>, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched the Sunny Suite for lipid nanoparticle (LNP) development today \u2013 Sunscreen<\/a> for screening formulations faster than ever before and Sunshine<\/a> for optimizing and scaling them up in no time.<\/p>\n

LNPs totally rock as vaccines and are the up-and-comer in gene therapy, but finding the perfect LNP formulation is no walk on the beach \u2013 it requires a massive amount of trial and error and can take an eternity. Researchers need to figure out the best lipid mixture, the right lipid to payload ratio and the optimal flow rates to mix them all up into an LNP. To make matters worse, it\u2019s usually done one experiment at a time. Once they find \u201cthe one\u201d it\u2019s straight to figuring out the process to scale it up, which likely means redeveloping the method from scratch \u2013 a task that would make anyone salty.<\/p>\n

Sunscreen helps researchers coast through LNP formulation, creating 96 unique, 200 \u00b5L \u2013 2 mL LNP formulations in less than 6 hours. They simply load one plate with lipids, the other with payloads, choose their flow rates and Sunscreen takes it from there. Once they\u2019re done digging up the primo formulation with Sunscreen, researchers can pass the protocol over to Sunshine to tune in their LNP size and design a stellar process to scale them up from microliter to liters \u2013 using the same reusable microfluidic device called the Sunny.<\/p>\n

“Developing the ideal LNP formulation doesn\u2019t have to be a long, painful process,\u201d said Taegen Clary, SVP of Marketing at Unchained Labs. \u201cWith the Sunny Suite, researchers can quickly dive deep into a larger LNP design space and then seamlessly scale them up. They should ditch the time-sucking, one by one, pay per use approaches and shine a light on their winners right away.\u201d<\/p>\n

About Unchained Labs<\/strong><\/p>\n

Here\u2019s the deal. We\u2019re all about helping biologics and gene therapy researchers break free from tools that just don\u2019t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That\u2019s our mantra, our promise and we own it. We\u2019re located in Pleasanton, CA and can be found online at unchainedlabs.com\/jp<\/a>.<\/p>\n

Contact:<\/strong>
\nTaegen Clary
\nSVP of Marketing, Unchained Labs
\nTaegen.clary@unchainedlabs.com\/jp<\/a>
\n925.587.9800<\/p>\n

Download PDF of the press release<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

October 3, 2023 \u2013 Pleasanton, CA \u2013 Unchained Labs, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched the Sunny Suite for lipid nanoparticle (LNP) development today \u2013 Sunscreen for screening formulations faster than ever before and Sunshine for optimizing and scaling them up…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[121],"tags":[],"class_list":["post-14504","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"yoast_head":"\nUnchained Labs makes waves in LNP formulation, launches the Sunny Suite! - unchainedlabs<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unchainedlabs.com\/jp\/unchained-labs-makes-waves-in-lnp-formulation-launches-the-sunny-suite\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Unchained Labs makes waves in LNP formulation, launches the Sunny Suite! 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