{"id":16058,"date":"2024-01-09T04:54:07","date_gmt":"2024-01-09T04:54:07","guid":{"rendered":"https:\/\/unchainedlabs.com\/jp\/?p=16058"},"modified":"2024-01-09T05:01:27","modified_gmt":"2024-01-09T05:01:27","slug":"unchained-labs-rolls-out-the-red-carpet-for-the-king-of-lnp-characterizationstunner","status":"publish","type":"post","link":"https:\/\/unchainedlabs.com\/jp\/unchained-labs-rolls-out-the-red-carpet-for-the-king-of-lnp-characterizationstunner\/","title":{"rendered":"Unchained Labs rolls out the red carpet for the king of LNP characterization\u2026Stunner!"},"content":{"rendered":"

January 9, 2024 \u2013 Pleasanton, CA \u2013 Unchained Labs<\/a>, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched a brand spanking new version of its hit product Stunner<\/a> today. Stunner is the first instrument of its kind for the characterization of lipid nanoparticles (LNPs), racking up sizing, particle concentration, payload concentration and LNP loading all from the same 2 \u00b5L sample \u2013 and to top it all off, in a 96-well plate format.<\/p>\n

LNPs are big, complicated molecules that have a lot to characterize \u2013 their size and uniformity, how many of them there are, the amount of total payload present, how much payload is in each particle and if they\u2019re aggregating. Getting all this data usually requires multiple instruments, lots of sample and is massively time consuming if a researcher is working through the trial and error of formulation screening or process development.<\/p>\n

Enter Stunner, the first instrument to pull all this LNP data together from one tiny 2 \u00b5L sample. Stunner uses rotating angle dynamic light scattering to measure LNPs from a bunch of angles to give researchers accurate sizing, particle concentration and a read on aggregation. In the same 2-minute experiment it uses UV\/Vis with precision of 1% and accuracy of 2% to quantify the total payload present. Then it combines payload and particle concentration to report out on loading. For the first time, researchers can rapidly take stock of their LNPs and make sure they\u2019re fully dialed in before testing how they function.<\/p>\n

\u201cOur new Stunner really is the cream of the crop for LNP characterization. It measures exactly what researchers need to find the best formulation and develop a robust process to make great LNPs.\u201d said Taegen Clary, SVP of Marketing at Unchained Labs. \u201cStunner also maintains all the applications it already had for biologics and AAVs, but now reports out molecular weight for proteins and is even more sensitive when it comes to tracking down aggregates. It\u2019s stunning, we know!\u201d<\/p>\n

About Unchained Labs<\/strong>
\nHere\u2019s the deal. We\u2019re all about helping biologics and gene therapy researchers break free from tools that just don\u2019t cut it. Unleashing problem-tackling solutions that make a huge difference in the real science they do every day. That\u2019s our mantra, our promise and we own it. We\u2019re located in Pleasanton, CA and can be found online at unchainedlabs.com\/jp<\/a>.<\/p>\n

Contact:<\/strong>
\nTaegen Clary
\nSVP of Marketing, Unchained Labs
\ntaegen.clary@unchainedlabs.com\/jp<\/a>
\n925.587.9806<\/p>\n

Download PDF of the press release<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

January 9, 2024 \u2013 Pleasanton, CA \u2013 Unchained Labs, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched a brand spanking new version of its hit product Stunner today. Stunner is the first instrument of its kind for the characterization of lipid nanoparticles (LNPs),…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[121],"tags":[],"class_list":["post-16058","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"yoast_head":"\nUnchained Labs rolls out the red carpet for the king of LNP characterization\u2026Stunner! - unchainedlabs<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unchainedlabs.com\/jp\/unchained-labs-rolls-out-the-red-carpet-for-the-king-of-lnp-characterizationstunner\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Unchained Labs rolls out the red carpet for the king of LNP characterization\u2026Stunner! - unchainedlabs\" \/>\n<meta property=\"og:description\" content=\"January 9, 2024 \u2013 Pleasanton, CA \u2013 Unchained Labs, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched a brand spanking new version of its hit product Stunner today. 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