{"id":29083,"date":"2026-07-07T00:22:37","date_gmt":"2026-07-07T00:22:37","guid":{"rendered":"https:\/\/unchainedlabs.com\/jp\/?p=29083"},"modified":"2026-07-14T00:25:56","modified_gmt":"2026-07-14T00:25:56","slug":"unchained-labs-sets-the-hook-on-automated-buffer-exchange-with-lil-tuna","status":"publish","type":"post","link":"https:\/\/unchainedlabs.com\/jp\/unchained-labs-sets-the-hook-on-automated-buffer-exchange-with-lil-tuna\/","title":{"rendered":"Unchained Labs Sets the Hook on Automated Buffer Exchange with Lil\u2019 Tuna"},"content":{"rendered":"<p><strong>July 7, 2026 \u2014 Pleasanton, CA \u2014<\/strong> <a href=\"http:\/\/unchainedlabs.com\">Unchained Labs<\/a>, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched Lil\u2019 Tuna today, the first fully automated, plate-based, benchtop buffer exchange system. Unchained\u2019s been automating buffer exchange forever \u2014 with Big Tuna for plate exchanges and Unagi for walk-up processing of individual samples. Lil\u2019 Tuna packs the best of both systems into one simple, compact, high-throughput buffer exchange platform perfect for every lab, at every scale.<\/p>\n<p>Buffer exchange and sample concentration are some of the most time-consuming, manual steps standing between researchers and the science they want to do. Traditional approaches using dialysis, centrifugation or cartridge-based filtration require constant intervention and are super hard to automate when going into screening mode. Teams using these methods are forced to micromanage a step that demands way too much of their attention and throttles throughput.<\/p>\n<p>Lil\u2019 Tuna uses the same exact pressure-based UF\/DF approach and consumables as Big Tuna and Unagi \u2013 processing 96- or 24-well plates for maximum throughput, handling one-off samples on the fly, and delivering recoveries \u226596%. For labs all in on automation, Lil\u2019 Tuna fits right in with API software, automation-friendly template importing and a sample stage designed for easy robotic access. It integrates directly with Stuntman, Unchained\u2019s AI-driven automation platform, for seamless handoff into formulation screening, stability characterization and other downstream workflows.<\/p>\n<p>\u201cBuffer exchange has always been one of those steps that kills a scientist\u2019s momentum,\u201d said Krystin Schmidt, VP Marketing, Unchained Labs. \u201cLil\u2019 Tuna fully automates the whole thing so researchers can finally stop babysitting their buffer exchange. Its compact footprint and automation-ready design make it a perfect fit for the next generation of AI-enabled labs.\u201d<\/p>\n<p><strong>About Unchained Labs<\/strong><\/p>\n<p>Here\u2019s the deal. We\u2019re all about helping biologics and gene therapy researchers break free from tools that just don\u2019t cut it. Unleashing problem-tackling solutions and AI-driven automation that make a huge difference in the real science they do every day. That\u2019s our mantra, our promise, and we own it. We\u2019re located in Pleasanton, CA and can be found online at <a href=\"http:\/\/unchainedlabs.com\">www.unchainedlabs.com<\/a>.<\/p>\n<p><strong>Contact<\/strong><\/p>\n<p>Krystin Schmidt<br \/>\nVP Marketing, Unchained Labs<br \/>\nkrystin.schmidt@unchainedlabs.com<br \/>\n925.392.5597<\/p>\n<p><a href=\"https:\/\/unchainedlabs.com\/jp\/wp-content\/uploads\/2026\/07\/Unchained-Labs-Sets-the-Hook-on-Automated-Buffer-Exchange-with-Lil-Tuna_Final.pdf\">Download PDF of the press release<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>July 7, 2026 \u2014 Pleasanton, CA \u2014 Unchained Labs, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched Lil\u2019 Tuna today, the first fully automated, plate-based, benchtop buffer exchange system. Unchained\u2019s been automating buffer exchange forever \u2014 with Big Tuna for plate exchanges and&hellip;<\/p>\n","protected":false},"author":329,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[121],"tags":[],"class_list":["post-29083","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Unchained Labs Sets the Hook on Automated Buffer Exchange with Lil\u2019 Tuna - unchainedlabs<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unchainedlabs.com\/jp\/unchained-labs-sets-the-hook-on-automated-buffer-exchange-with-lil-tuna\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Unchained Labs Sets the Hook on Automated Buffer Exchange with Lil\u2019 Tuna - unchainedlabs\" \/>\n<meta property=\"og:description\" content=\"July 7, 2026 \u2014 Pleasanton, CA \u2014 Unchained Labs, the life sciences company that\u2019s all about getting biologics and gene therapy researchers the right tool for the job, launched Lil\u2019 Tuna today, the first fully automated, plate-based, benchtop buffer exchange system. 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