{"id":7216,"date":"2020-04-01T19:57:27","date_gmt":"2020-04-01T19:57:27","guid":{"rendered":"https:\/\/unchainedlabs.com\/jp\/?post_type=post&p=7216"},"modified":"2023-10-05T07:17:17","modified_gmt":"2023-10-05T07:17:17","slug":"unchained-labs-jumps-into-gene-therapy-and-vaccines-with-new-aav-stability-application","status":"publish","type":"post","link":"https:\/\/unchainedlabs.com\/jp\/unchained-labs-jumps-into-gene-therapy-and-vaccines-with-new-aav-stability-application\/","title":{"rendered":"Unchained Labs jumps into gene therapy and vaccines with new AAV stability application!"},"content":{"rendered":"

April 1, 2020 \u2013 Pleasanton, CA \u2013\u00a0Unchained Labs<\/a>, the life sciences company that\u2019s all about getting biologics researchers the right tool for the job, launched its new AAV stability application on the Uncle<\/a> platform today. Uncle is already the gold standard for measuring protein stability and, with this new application, jumps in to support researchers in pursuit of novel gene therapies and better vaccines.<\/p>\n

Many gene therapies, immunotherapies and vaccines being developed use adeno-associated viruses or AAVs. These viral vectors are great at sneaking past the body\u2019s immune system to deliver DNA that commands cells to make proteins that end diseases or antibodies that seek out and destroy viruses. A stable AAV stays intact until it finds its target and won\u2019t aggregate \u2013 or worse, leak potentially toxic DNA into the body.<\/p>\n

Uncle\u2019s newest application helps researchers understand their AAV stability. It uses a thermal ramp with a DNA-binding fluorescent dye to help them get a read on when DNA starts to leak from an AAV, even before the capsid starts to fall apart. Uncle\u2019s DLS and SLS combo can measure the particle titer to see how many capsids they have. They\u2019ll also know when aggregation gets out of hand.<\/p>\n

\u201cWith this new application, Uncle lends a helping hand to researchers working on life-changing gene therapies and vaccines,\u201d said Taegen Clary, VP of Marketing at Unchained Labs. \u201cWith deeper insights into AAV stability, researchers can now screen and refine their capsids for strength, find the best formulations, and optimize storage conditions, all with a single instrument.\u201d<\/p>\n

About Unchained Labs<\/strong><\/p>\n

Here\u2019s the deal. We\u2019re all about helping biologics researchers break free from tools that just don\u2019t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That\u2019s our mantra, our promise and we own it. We\u2019re located in Pleasanton, CA and can be found online at unchainedlabs.com\/jp<\/a>.<\/p>\n

Contact:<\/strong><\/p>\n

Taegen Clary
\nVP of Marketing, Unchained Labs
\ntaegen.clary@unchainedlabs.com\/jp<\/a>
\n925.587.9806<\/p>\n

Download PDF of the press release<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

April 1, 2020 \u2013 Pleasanton, CA \u2013\u00a0Unchained Labs, the life sciences company that\u2019s all about getting biologics researchers the right tool for the job, launched its new AAV stability application on the Uncle platform today. 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